The two zones of water injection after X well repair in Bozhong 25⁃1 oilfield are confronted with two major problems. First, the injection pressure difference between two layers is 18 MPa, and secondly, the application of steel wire or coiled tubing is used to replace the horizon. The operation cycle is long and the cost is high. In order to solve the above problem, a new type of non⁃throwing fishing periodic water injection technology is applied, and the underground water injection level and water injection volume are adjusted by surface hydraulic control. The optimum design of sand control pipe string and water injection pipe string is matched to replace repeated steel wire operation. The problem has been solved, which guarantees the safety of water injection operation in high pressure differential layer, and saves 100% of the time and cost of steel wire allocation.